International Journal of Emerging Research in Science, Engineering, and Management
Vol. 1, Issue 2, pp. 26-31, August 2025.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Comparative Study of Antimicrobial Resistance in Urban vs Rural Areas
Nupura Joshi
Assistant Professor, Department of Microbiology, Abasaheb Garware College, Pune, India.
Abstract: Antimicrobial resistance (AMR) is a growing global health concern, driven by complex interactions across clinical, environmental, and socioeconomic domains. While much research has focused on AMR prevalence in urban healthcare settings, rural environments—often lacking structured surveillance—are emerging as critical reservoirs of resistance genes. This paper presents a comparative study of AMR patterns in urban versus rural areas, synthesizing recent research on clinical isolates, environmental samples, livestock-associated resistance, and socio-behavioral drivers. The analysis reveals higher detection of extended-spectrum beta-lactamase (ESBL) and carbapenem-resistant organisms in urban hospitals, while rural regions show elevated levels of environmental and zoonotic transmission of resistant bacteria, often linked to agricultural runoff, poor waste management, and informal antibiotic use. Socioeconomic disparities further exacerbate resistance by varying hygiene, healthcare access, and awareness. The study underscores the importance of adopting a One Health approach and improving AMR surveillance and stewardship strategies tailored to the specific risks of both urban and rural contexts.
Keywords: Antimicrobial resistance, One Health, Rural health, Socioeconomic factors, Urban-rural comparison.
References:
- G. Ljungqvist et al., “Mapping socioeconomic factors driving antimicrobial resistance in humans: An umbrella review,” One Health, vol. 20, p. 100986, Feb. 2025, doi: 10.1016/j.onehlt.2025.100986.
- K. Robins, G. O’Donnell, A. Neumann, W. Schmidt, A. Hart, and D. W. Graham, “Antimicrobial resistance in rural rivers: Comparative study of the Coquet (Northumberland) and Eden (Cumbria) River catchments,” The Science of the Total Environment, vol. 928, p. 172348, Apr. 2024, doi: 10.1016/j.scitotenv.2024.172348.
- F. Naznine, Z. Shafi, U. Aafreen, M. Shahid, S. Parveen, and M. I. Ansari, “Tracking antimicrobial resistance in river waters: sources, key microbes, and detection techniques,” The Microbe, p. 100386, May 2025, doi: 10.1016/j.microb.2025.100386.
- I. Mbatidde et al., “Antimicrobial use and antimicrobial resistance in Escherichia coli in semi-intensive and free-range poultry farms in Uganda,” One Health, vol. 18, p. 100762, May 2024, doi: 10.1016/j.onehlt.2024.100762.
- M. S. ALjohni, M. Harun-Ur-Rashid, and S. Selim, “Emerging Threats: Antimicrobial Resistance in Extended-Spectrum Beta-Lactamase and Carbapenem-Resistant Escherichia coli,” Microbial Pathogenesis, p. 107275, Jan. 2025, doi: 10.1016/j.micpath.2024.107275.
- M. W. Gach et al., “Antimicrobial resistance among common bacterial pathogens in Indonesia: a systematic review,” The Lancet Regional Health – Southeast Asia, vol. 26, p. 100414, May 2024, doi: 10.1016/j.lansea.2024.100414.
- J. K. Calland et al., “Population structure and antimicrobial resistance among Klebsiella isolates sampled from human, animal, and environmental sources in Ghana: a cross-sectional genomic One Health study,” The Lancet Microbe, vol. 4, no. 11, pp. e943–e952, Oct. 2023, doi: 10.1016/s2666-5247(23)00208-2.
- M. Verma et al., “Antimicrobial stewardship programme in a trauma centre of a tertiary care hospital in North India: Effects and implementation challenges,” Journal of Global Antimicrobial Resistance, vol. 17, pp. 283–290, Mar. 2019, doi: 10.1016/j.jgar.2019.02.020.
- Y. Wu et al., “Predicting Relative Risk of Antimicrobial Resistance using Machine Learning Methods,” IFAC-PapersOnLine, vol. 55, no. 10, pp. 1266–1271, Jan. 2022, doi: 10.1016/j.ifacol.2022.09.564.
- M. -U. Alam et al., “Human exposure to antimicrobial resistance from poultry production: Assessing hygiene and waste-disposal practices in Bangladesh,” International Journal of Hygiene and Environmental Health, vol. 222, no. 8, pp. 1068–1076, Jul. 2019, doi: 10.1016/j.ijheh.2019.07.007.
- J. Seni et al., “Multicentre evaluation of significant bacteriuria among pregnant women in the cascade of referral healthcare system in North-western Tanzania: Bacterial pathogens, antimicrobial resistance profiles and predictors,” Journal of Global Antimicrobial Resistance, vol. 17, pp. 173–179, Jan. 2019, doi: 10.1016/j.jgar.2018.12.024.
- Nikita Pathak, Alok Kumar Srivastav, “Antimicrobial Activity of Selected Medicinal Plants from Around Ujjain City, India,” International Journal of Emerging Research in Engineering, Science, and Management, vol. 3, no. 4, pp. 57-61, 2024. doi: 10.58482/ijeresm.v3i4.8.
